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KMID : 0191120220370130104
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Journal of Korean Medical Science
2022 Volume.37 No. 13 p.104 ~ p.104
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A Case of Heart Transplantation for Fulminant Myocarditis After ChAdOx1 nCoV-19 Vaccination
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Kim Seok-Hyun
Lee Soo-Yong
Kim Ga-Yun
Oh Ji-Soo
Kim Jeong-Su
Chun Kook-Jin
Ju Min-Ho
Lee Chee-Hoon
Song Yeo-Jeong
Na Joo-Young
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Abstract
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Vaccines have become the mainstay of management against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019; COVID-19) in the absence of effective antiviral therapy. Various adverse effects of COVID-19 vaccination have been reported, including cardiovascular complications such as myocarditis or pericarditis. Herein, we describe clinical records of a 63-year woman with fulminant myocarditis following ChAdOx1 nCoV-19 vaccination that was salvaged by heart transplantation. She complained chest pain, nausea, vomiting, and fever after the second vaccination. After the heart transplantation, the patient died due to necrotizing pneumonia on the 54th day of onset. Fulminant myocarditis is very rare after ChAdOx1 nCoV-19 vaccination but can be fatal.
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KEYWORD
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ChAdOx1 nCoV-19 Vaccine, Myocarditis, COVID-19, AstraZeneca
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